Oncology · Public Health · 58 min ago
Lifetime cancer risks reveal geographic inequalities in male genital cancers
A population-based analysis of GLOBOCAN 2022 data estimated lifetime risks of penile, prostate and testicular cancers across 185 countries. The study found substantial regional and socioeconomic differences, and reported that the conventional cumulative risk measure to age 74 understated inequalities, particularly for late-onset cancers.
- Lifetime incidence risk was 4.250% in 2022.
- Burden varied substantially across regions and HDI levels.
- Risk to age 74 understated some inequalities.
- Analysis used GLOBOCAN 2022 data from 185 countries.
Researchers used GLOBOCAN 2022 data from 185 countries to estimate lifetime incidence and mortality risks for penile, prostate and testicular cancers, collectively termed male genital cancers. They applied an adjusted multiple-primary method and assessed inequality across Human Development Index levels using concentration indices, comparing lifetime risk with cumulative risk to age 74.
In 2022, the combined lifetime incidence risk was 4.250% and the mortality risk was 1.358%. Risks were highest in Northern Europe, Australia and New Zealand, and Western Europe, and lowest in Africa. The authors found that the burden was concentrated in higher-HDI countries, which they suggest may relate to differences in health-resource allocation. The age-74 cumulative risk measure understated inequality compared with lifetime risk, especially for penile and prostate cancers.
This analysis describes population-level patterns and does not establish why the disparities occur. Its estimates depend on GLOBOCAN data and the methods used to calculate lifetime risk; the findings do not indicate individual risk or establish the effects of specific interventions. The authors call for health actions addressing inequalities and broader use of lifetime risk as a burden indicator.
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BMC Public Health: Global burden inequality in lifetime risk of penile, prostate, and testicular cancers: a population-based systematic analysis of GLOBOCAN 2022 ↗This is an automated AI-condensed summary that has not yet been reviewed by an editor. Always consult the full item at the original source.