Gastroenterology · Pediatrics · 53 min ago
Nationwide study estimates celiac disease prevalence in French children at 0.15%
A nationwide observational study used French health data to identify 41,690 children diagnosed with celiac disease between 2011 and 2022. The estimated prevalence in 2022 was 0.15%, with variation across regions; the authors note that administrative and serological data were used to identify cases.
- 2022 prevalence was estimated at 0.15%.
- Regional estimates ranged from 0.08% to 0.25%.
- The analysis identified 41,690 children over 12 years.
- Case identification relied on health-system records and test patterns.
Researchers analyzed the French National Health Data System to identify children under 18 with celiac disease from 2011 through 2022. Cases were defined by a celiac disease hospitalization, long-term disease status, or a specified sequence of transglutaminase and endomysium antibody tests. The study identified 41,690 children, with a male-to-female ratio of 0.88.
In 2022, estimated prevalence was 0.15% nationally, ranging from 0.08% in north-western France to 0.25% in the south-east. Annual incidence ranged from 12.4 per 100,000 children in 2020 to 17.4 in 2012. Median age at diagnosis increased from six years in 2011 to seven in 2015. Reported comorbidities included type 1 diabetes in 9.7% and thyroid disease in 1.7%.
The authors describe prevalence as lower than in other European countries and suggest these data may inform consideration of celiac disease in older children with atypical signs. This was an observational analysis of health-system data, not a population screening study; case identification depended on recorded diagnoses and test patterns. The study received a grant from the French Association of Gluten Intolerants, which the authors say had no role in the research or publication decision.
Is this summary clinically accurate?
Help fellow clinicians: your rating sends inaccurate summaries straight to our editors.
Sign in to rate this summary →Source
Pediatric Research: Low prevalence of celiac disease in French children, a nationwide study ↗This is an automated AI-condensed summary that has not yet been reviewed by an editor. Always consult the full item at the original source.