Cardiology · Obstetrics & Gynecology · General Practice · 3 h ago
Danish cohort identifies cardiovascular risk markers after preeclampsia
A Danish nationwide registry cohort followed 17,434 women with preeclampsia after their first delivery; 2,372 subsequently developed chronic hypertension and 373 developed cardiovascular disease. Higher BMI, older maternal age and lower education were associated with higher incidence rates, although several diabetes- and smoking-related cardiovascular estimates were imprecise.
- Among 17,434 women, 2,372 developed hypertension and 373 developed CVD.
- Lower education was associated with higher hypertension and CVD rates.
- Rates increased with higher BMI and older maternal age.
- Several smoking- and diabetes-related CVD estimates were imprecise.
A nationwide Danish register-based cohort examined factors associated with chronic hypertension and cardiovascular disease (CVD) after preeclampsia. Researchers followed 17,434 primiparous women with preeclampsia who delivered during 2004–2018 until December 2022, using Poisson regression to estimate incidence rate ratios (IRRs) for both outcomes.
During follow-up, 2,372 women developed chronic hypertension and 373 developed CVD. Early-onset preeclampsia was more frequent among women who subsequently developed hypertension than among those who did not (13.3% versus 7.4%); corresponding proportions for CVD were 12.1% versus 8.1%. Lower education was associated with higher rates of hypertension (IRR 1.50, 95% CI 1.31–1.72) and CVD (2.77, 1.92–3.98). Smoking during pregnancy, gestational diabetes and pre-existing type 1 diabetes were also associated with higher hypertension rates. Incidence rates increased with BMI and maternal age, more steeply above 25 kg/m² and 40 years.
The findings may help inform cardiovascular risk assessment after preeclampsia, but they do not establish that targeted prevention improves outcomes. CVD estimates for smoking and diabetes had confidence intervals crossing 1, limiting certainty about these associations. This observational analysis is available here only as an abstract; details of covariate adjustment and outcome definitions could not be assessed.
Is this summary clinically accurate?
Help fellow clinicians: your rating sends inaccurate summaries straight to our editors.
Sign in to rate this summary →Source
European Journal of Preventive Cardiology: Chronic Hypertension and Cardiovascular Disease After Preeclampsia: A Danish Nationwide Register-Based Cohort Study Identifying Women at High Risk ↗This is an automated AI-condensed summary that has not yet been reviewed by an editor. Always consult the full item at the original source.