ACOG Guideline Addresses Menopause-Related Vasomotor, Sleep, and Mood Symptoms

An ACOG clinical practice guideline published in Obstetrics & Gynecology addresses vasomotor, sleep, and mood symptoms associated with spontaneous or induced menopause at or beyond age 40 years. Its target population includes perimenopausal and postmenopausal individuals assigned female sex at birth, including women, transgender men, and gender-diverse individuals.

The writing team used a prespecified protocol, with two authors assessing studies reaching full-text screening against standardized inclusion and exclusion criteria. Included studies underwent quality assessment. A modified GRADE evidence-to-decision framework was used to translate the evidence into recommendations covering pharmacologic and nonpharmacologic interventions, classified by recommendation strength and evidence quality.

The guideline also includes ungraded Good Practice Points where evidence was inadequate or absent. Although relevant to menopause care in specialist and primary-care settings, the supplied abstract does not identify recommended treatments, effect estimates, or individual recommendation grades. The full guideline is needed to establish its implications for treatment selection.